Lecturers who have so far agreed to speak at the 2014 SEMRC:
Prof. Wolfgang Lubitz
Director, Department of Biophysical Chemistry
Max Planck Institute for Chemical Energy Conversion
Mülheim an der Ruhr, Germany
Metalloproteins and bioinorganic model complexes are investigated that are related to energy conserving systems. In focus are the water oxidizing enzyme of oxygenic photosynthesis and hydrogenases. We use a variety of different physical techniques to study them, including electrochemistry, X-ray crystallography, magnetic resonance, Mößbauer as well as time resolved optical and vibrational spectroscopy. Particular emphasis is placed on paramagnetic molecules studied by advanced EPR techniques.
Howard J. Halpern, MD, PhD
Professor of Radiation and Cellular Oncology
Director, Center for EPR Imaging In Vivo Physiology
The University of Chicago Chicago, Illinois
Development of new imaging technologies sensitive to the functioning of the normal and diseased tissues of living animals for accurate and efficient imaging of molecular oxygen concentration in tissues. The Center’s imaging technology exploits the unique, quantitative sensitivity of the EPR spectrum of soluble, injectable spin probes to crucial aspects of the fluids in which life processes evolve. Low frequency EPR technology is used to maximize the depth in animal tissue to which the technique is sensitive.
Prof. Michael A. Kennedy
Ohio Eminent Scholar
Professor of Chemistry and Biochemistry
NMR- and MS- Based Metabonomics measurement of changes in an organism’s metabolic profile in response to external stimuli, genetic modifications, or as a consequence of presence or severity of disease. NMR-Based Structural Genomics is being used to determine the 3D structures of functionally uncharacterized proteins whose sequences are not similar to the sequence of any protein whose structure is known. With the structure of an uncharacterized protein, one can begin to understand its function according to structure-function principles.
Prof. Arthur Roberts
Assistant Professor, Pharmaceutical and Biomedical Sciences
College of Pharmacy
University of Georgia
Utilizes advanced NMR techniques in studying the interaction of drugs with multiple-drug resistance transporters and drug-metabolizing UDP-glucuronosyltransferases. These proteins play major roles in cancer resistance, in neurological diseases (e.g. Alzheimer’s disease and Parkinson’s) and in mitigating the effects of environmental pollutants. Using human proteins isolated from genetically engineered yeast or bacteria, one goal is to develop structural biology tools to rapidly and accurately predict the effects of drugs and toxins before they end up in people.
Robert D. McMichael, PhD
Project Leader Electron Physics Group, Center for Nanoscale Science and Technology
National Institute of Standards and Technology
Research touches on a broad spectrum of phenomena in magnetic thin films and nanomaterials, but remains centered on micromagnetics and magnetization dynamics.